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Manufacturing 5.0: MES, AI, and Human-Centric Digital Factories

Manufacturing 5.0: MES, AI, and Human-Centric Digital Factories

Manufacturing is entering a new era—one that goes beyond automation and efficiency to place people at the centre of digital transformation. Manufacturing 5.0 represents the evolution of Industry 4.0 by combining advanced technologies such as Manufacturing Execution Systems (MES), artificial intelligence (AI), and smart automation with human creativity, judgement, and collaboration. In this model, MES acts as the digital backbone of the factory, capturing real-time production data, synchronising shop-floor operations with enterprise systems, and enabling traceability and data-driven decision-making. AI builds on this foundation by delivering predictive insights, intelligent scheduling, anomaly detection, and continuous optimisation across production, maintenance, and logistics. At the same time, Manufacturing 5.0 emphasises human-centric design—empowering workers with assistive technologies, intuitive interfaces, collaborative robots, and safer, more ergonomic environments. The digital factory of this new era is characterised by connected IoT systems, digital twins, cyber-physical integration, cloud connectivity, edge computing, and sustainability intelligence that supports energy efficiency and ESG goals. Rather than replacing people, technology augments human capabilities, enabling faster decisions, greater resilience, and more adaptive operations. Manufacturing 5.0 is not just a technological shift—it is a strategic mindset focused on smarter, more sustainable, and more inclusive production systems. To help visualise the core pillars and key features of Manufacturing 5.0, we’ve summarised this evolution in the infographic below.

Manufacturing 5.0 MES, AI, and Human-Centric Digital Factories

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